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The study revealed several alterations that affect the course of CVD

While nitrate (NO) itself is relatively inert and does not directly cause oxidative or nitrosative stress, it is considered an important storage and endproduct of nitrogen-based redox reactions

The LAT subunits are members of the amino acid polyamine cation (APC) superfamily 32 , which exhibit a conserved 5 + 5 inverted topology fold, wherein the first five TM helices are related to the second five helices via a pseudo two-fold symmetry axis running parallel to the plane of the membrane 33

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